Aptamers Selected for Recognizing Amyloid beta-Protein-A Case for Cautious Optimism
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Description
Aptamers are versatile oligonucleotide ligands used for molecular recognition of diverse targets. However, application of aptamers to the field of amyloid beta-protein (A beta) has been limited so far. A beta is an intrinsically disordered protein that exists in a dynamic conformational equilibrium, presenting time-dependent ensembles of short-lived, metastable structures and assemblies that have been generally difficult to isolate and characterize. Moreover, despite understanding of potential...[Show more]
Collections | ANU Research Publications |
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Date published: | 2018 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/164185 |
Source: | International Journal of Molecular Sciences |
DOI: | 10.3390/ijms19030668 |
Access Rights: | Open Access |
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01_Rahimi_Aptamers_Selected_for_2018.pdf | 460.15 kB | Adobe PDF |
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