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Aptamers Selected for Recognizing Amyloid beta-Protein-A Case for Cautious Optimism

Rahimi, Farid

Description

Aptamers are versatile oligonucleotide ligands used for molecular recognition of diverse targets. However, application of aptamers to the field of amyloid beta-protein (A beta) has been limited so far. A beta is an intrinsically disordered protein that exists in a dynamic conformational equilibrium, presenting time-dependent ensembles of short-lived, metastable structures and assemblies that have been generally difficult to isolate and characterize. Moreover, despite understanding of potential...[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
URI: http://hdl.handle.net/1885/164185
Source: International Journal of Molecular Sciences
DOI: 10.3390/ijms19030668
Access Rights: Open Access

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