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Vitamin D-Binding Protein Polymorphisms, 25-Hydroxyvitamin D, Sunshine and Multiple Sclerosis

Langer_Gould, Annette; Lucas, Robyn; Xiang, Anny; Wu, Jun; Chen, Lie H; Gonzales, Edlin; Haraszti, Samantha; Smith, Jessica B; Quach, Hong; Barcellos, Lisa F


Blacks have different dominant polymorphisms in the vitamin D-binding protein (DBP) gene that result in higher bioavailable vitamin D than whites. This study tested whether the lack of association between 25-hydroxyvitamin D (25OHD) and multiple sclerosis (MS) risk in blacks and Hispanics is due to differences in these common polymorphisms (rs7041, rs4588). We recruited incident MS cases and controls (blacks 116 cases/131 controls; Hispanics 183/197; whites 247/267) from Kaiser Permanente...[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
Source: Nutrients
DOI: 10.3390/nu10020184.
Access Rights: Open Access


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