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miRA: adaptable novel miRNA identification in plants using small RNA sequencing data

Evers, Maurits; Huttner, Michael; Dueck, Anne; Meister, Gunter; Engelmann, Julia C

Description

BACKGROUND: MicroRNAs (miRNAs) are short regulatory RNAs derived from longer precursor RNAs. miRNA biogenesis has been studied in animals and plants, recently elucidating more complex aspects, such as non-conserved, species-specific, and heterogeneous miRNA precursor populations. Small RNA sequencing data can help in computationally identifying genomic loci of miRNA precursors. The challenge is to predict a valid miRNA precursor from inhomogeneous read coverage from a complex...[Show more]

CollectionsANU Research Publications
Date published: 2015-11-05
Type: Journal article
URI: http://dx.doi.org/10.1186/s12859-015-0798-3
http://hdl.handle.net/1885/16372
Source: BMC Bioinformatics
DOI: 10.1186/s12859-015-0798-3

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