Skip navigation
Skip navigation

Increased antigen specific T cell numbers in the absence of altered migration or division rates as a result of mucosal cholera toxin administration

Kaparakis-Liaskos, Maria; Tate, Michelle D.; Price, Jason D.; Pearse, Martin; Wijburg, Odilia L. C.

Description

Cholera toxin (CT) is a mucosal adjuvant capable of inducing strong immune responses to co-administered antigens following oral or intranasal immunization of mice. To date, the direct effect of CT on antigen-specific CD4(+) T cell migration and proliferation profiles in vivo is not well characterized. In this study, the effect of CT on the migration pattern and proliferative responses of adoptively transferred, CD4(+) TCR transgenic T cells in orally or intranasally vaccinated mice, was...[Show more]

CollectionsANU Research Publications
Date published: 2013-03-27
Type: Journal article
URI: http://hdl.handle.net/1885/16148
Source: PLoS ONE
DOI: 10.1371/journal.pone.0059934

Download

File Description SizeFormat Image
01_Kaparakis-Liaskos_Increased_antigen_specific_T_2013.pdfPublished Version627.23 kBAdobe PDFThumbnail


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  12 November 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator