Skip navigation
Skip navigation

The intracellular HBV DNAs as novel and sensitive biomarkers for the clinical diagnosis of occult HBV infection in HBeAg negative hepatocellular carcinoma in China

Wang, Hui; Fang, Meng; Gu, Xing; Ji, Qiang; Li, Dongdi; Cheng, Shu-Qun; Shen, Feng; Gao, Chun-Fang


This study aimed to investigate the virological status in liver (both tumor and adjacent non-tumor tissue), the clinical features and the contribution of occult HBV infection (OBI) to postoperative prognosis in HBeAg-negative(-) hepatocellular carcinoma (HCC) patients in China. Using quantitative TaqMan fluorescent real-time PCR assays, HBV covalently closed circular DNA (cccDNA) and total DNA (tDNA) were both quantified in 11 (HBsAg(-)) and 57 (HBsAg-positive(+)) pairs of tumor tissue (TT) and...[Show more]

CollectionsANU Research Publications
Date published: 2014-09-17
Type: Journal article
Source: PLoS ONE
DOI: 10.1371/journal.pone.0107162


File Description SizeFormat Image
01_Wang_The_intracellular_HBV_DNAs_as_2014.pdfPublished Version324.31 kBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator