Regulation of Peptide Hormones.
C-Terminal amidated peptide hormones regulate numerous physiological process and are associated with many pathological conditions. Their C-terminal amidation is exclusively catalysed by the enzyme peptidylglycine alpha-amidating monooxygenase (PAM), which has two subunits: peptidylglycine alpha-hydroxylating monooxygenase (PHM; EC 220.127.116.11) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL; EC 18.104.22.168). In the present study, the substrate specificity and inhibition of the PAM...[Show more]
|Collections||Open Access Theses|
|Chen Gu-PhD Thesis May 2019.pdf||Thesis Material||15.5 MB||Adobe PDF|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.