Altered regulatory T-cell fractions and Helios expression in clinically isolated syndrome: clues to the development of multiple sclerosis
Development of multiple sclerosis (MS) is frequently preceded by an acute or subacute neurological disturbance referred to as clinically isolated syndrome (CIS). The specific immunological disturbances present in CIS remain underexamined. This study analysed peripheral blood mononuclear cells from n = 18 treatment-naive individuals with recently diagnosed CIS (< 120 days) for disturbances in the phenotype of T regulatory (Treg), follicular T regulatory (Tfr), T helper (Th), follicular T helper...[Show more]
|Collections||ANU Research Publications|
|Source:||Clinical and Translational Immunology|
|Access Rights:||Open Access|
|01_Jones_Altered_regulatory_T-cell_2017.pdf||1.62 MB||Adobe PDF|
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