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Decarboxylative couplings as versatile tools for late-stage peptide modifications

Malins, Lara


While strategies for the late‐stage modification of peptides are crucial to the design and synthesis of new peptide‐based materials and therapeutics, synthetic methods have historically focused on the modification of select, nucleophilic amino acids. This review highlights decarboxylative coupling strategies as emerging tools for the targeted functionalization of native peptidic acids—α‐carboxylic acids and aspartic/glutamic acid residues—through complexity building CC and Cheteroatom bond...[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
Source: Peptide Science
DOI: 10.1002/pep2.24049


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