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Rapid and selective sampling of IgG from skin in less than 1 min using a high surface area wearable immunoassay patch

Coffey, Jacob W; Corrie, Simon R; Kendall, Mark

Description

Microprojection array (MPA) patches are an attractive approach to selectively capture circulating proteins from the skin with minimal invasiveness for diagnostics at the point-of-care or in the home. A key challenge to develop this technology is to extract sufficient quantities of specific proteins from within the skin to enable high diagnostic sensitivity within a convenient amount of time. To achieve this, we investigated the effect of MPA geometry (i.e. projection density, length and array...[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
URI: http://hdl.handle.net/1885/160487
Source: Biomaterials
DOI: 10.1016/j.biomaterials.2018.03.039

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