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Rapid sample delivery for megahertz serial crystallography at X-ray FELs

Wiedorn, Max; Awel, Salah; Morgan, A; Ayyer, Kartik; Gevorkov, Yaroslav; Fleckenstein, Holger; Roth, N; Adriano, L; Bean, R; Beyerlein, K. R.; Rode, Andrei V


Liquid microjets are a common means of delivering protein crystals to the focus of X-ray free-electron lasers (FELs) for serial femtosecond crystallography measurements. The high X-ray intensity in the focus initiates an explosion of the microjet and sample. With the advent of X-ray FELs with megahertz rates, the typical velocities of these jets must be increased significantly in order to replenish the damaged material in time for the subsequent measurement with the next X-ray pulse. This work...[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
Source: IUCrJ
DOI: 10.1107/S2052252518008369
Access Rights: Open Access


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