Skip navigation
Skip navigation

Design and synthesis of new functionalized isoindigo and (3Z,3 ' Z)-3,3 '-(ethane-1,2-diylidene)bis(indolin-2-one) derivatives

Khalili, Gholamhossein; Willis, Anthony; Keller, Paul


A library of N,N-substituted isoindigo derivatives were prepared by reaction of isoindigo with a variety of alkylating agents in the presence of MeONa under mild conditions in yields of 65–80%. A new, more efficient synthesis of (3Z,3′Z)-3,3′-(ethane-1,2-diylidene)bis(indolin-2-one) is described by reaction of oxindole with glyoxal at reflux in methanol—a small library of N,N′-substituted derivatives were also prepared in 60–70% yield.

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
Source: Monatshefte fur Chemie
DOI: 10.1007/s00706-018-2272-1


File Description SizeFormat Image
01_Khalili_Design_and_synthesis_of_new_2018.pdf835.74 kBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator