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Seroprevalence and spatial epidemiology of Lymphatic Filariasis in American Samoa after successful mass drug administration

Lau, Colleen L.; Won, Kimberly Y.; Becker, Luke; Soares Magalhaes, Ricardo; Fuimaono, Saipale; Melrose, Wayne; Lammie, Patrick J.; Graves, Patricia M.


BACKGROUND As part of the Global Programme to Eliminate Lymphatic Filariasis (LF), American Samoa conducted mass drug administration (MDA) from 2000-2006, and passed transmission assessment surveys in 2011-2012. We examined the seroprevalence and spatial epidemiology of LF post-MDA to inform strategies for ongoing surveillance and to reduce resurgence risk. METHODS ELISA for LF antigen (Og4C3) and antibodies (Wb123, Bm14) were performed on a geo-referenced serum bank of 807 adults collected in...[Show more]

CollectionsANU Research Publications
Date published: 2014-11-13
Type: Journal article
Source: PLoS Neglected Tropical Diseases
DOI: 10.1371/journal.pntd.0003297


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