Cytosolic Recognition of Microbes and Pathogens: Inflammasomes in Action
Infection is a dynamic biological process underpinned by a complex interplay between the pathogen and the host. Microbes from all domains of life, including bacteria, viruses, fungi, and protozoan parasites, have the capacity to cause infection. Infection is sensed by the host, which often leads to activation of the inflammasome, a cytosolic macromolecular signaling platform that mediates the release of the proinflammatory cytokines interleukin-1β (IL-1β) and IL-18 and cleavage of the...[Show more]
|Collections||ANU Research Publications|
|Source:||Microbiology and Molecular Biology Reviews|
|Access Rights:||Open Access|
|Hayward et al 2017 MMBR.pdf||992.34 kB||Adobe PDF|
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