Epiandrosterone sulfate prolongs the detectability of testosterone, 4-androstenedione, and dihydrotestosterone misuse by means of carbon isotope ratio mass spectrometry
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Piper, Thomas; Putz, Marlen; Schänzer, Wilhelm; Pop, Valentin; McLeod, Malcolm; Uduwela, Dimanthi; Stevenson, Bradley; Thevis, Mario
Description
In the course of investigations into the metabolism of testosterone (T) by means of deuterated T and hydrogen isotope ratio mass spectrometry, a pronounced influence of the oral administration of T on sulfoconjugated steroid metabolites was observed. Especially in case of epiandrosterone sulfate (EPIA_S), the contribution of exogenous T to the urinary metabolite was traceable up to 8 days after a single oral dose of 40 mg of T. These findings initiated follow-up studies on the capability of...[Show more]
Collections | ANU Research Publications |
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Date published: | 2017 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/159360 |
Source: | Drug Testing and Analysis |
DOI: | 10.1002/dta.2291 |
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