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1H, 13C and 15N backbone NMR chemical shift assignments of the C-terminal P4 domain of Ahnak

Sundararaj, Srinivasan; Shishmarev, Dmitry S.; Lin, Yiechang; Aditya, Shouvik; Casarotto, Marco


Ahnak is a ~ 700 kDa polypeptide that was originally identified as a tumour-related nuclear phosphoprotein, but later recognized to play a variety of diverse physiological roles related to cell architecture and migration. A critical function of Ahnak is modulation of Ca2+ signaling in cardiomyocytes by interacting with the β subunit of the L-type Ca2+ channel (CaV1.2). Previous studies have identified the C-terminal region of Ahnak, designated as P3 and P4 domains, as a key mediator of its...[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
Source: Biomolecular NMR Assignments
DOI: 10.1007/s12104-018-9818-3


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