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Effect of SSRI and calcium channel blockers on depression symptoms and cognitive function in elderly persons treated for hypertension: three city cohort study

Tully, Phillip J.; Peters, Ruth; Pérès, Karine; Anstey, Kaarin; Tzourio, Christophe

Description

Background: Emerging genetic, ex-vivo, and clinical trial evidence indicates that calcium channel blockers (CCB) can improve mood and cognitive function. The objective of this study was to examine the effect of selective serotonin reuptake inhibitor (SSRI) therapy augmented with CCB on depression and cognitive decline in an elderly population with hypertension. Methods: Prospective study of 296 persons treated with SSRI and antihypertensive drugs. Baseline and two year clinic assessments...[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
URI: http://hdl.handle.net/1885/159349
Source: International Psychogeriatrics
DOI: 10.1017/S1041610217002903

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