Skip navigation
Skip navigation

Total Syntheses of the Amaryllidaceae Alkaloids Zephycandidine III and Lycosinine A and Their Evaluation as Inhibitors of Acetylcholinesterase

Xu, Xingjun; Kim, Hye; Chen, Weimin; Ma, Xiang; Correy, Galen; Banwell, Martin; Jackson, Colin; Willis, Anthony; Carr, Paul D

Description

The title alkaloids, 1 and 2, have been prepared using cross-coupling chemistries and together with various analogues they have been evaluated for their capacity to inhibit acetylcholinesterase. Contrary to an earlier report, it was found that biaryl 1 is not a significant inhibitor of this enzyme, and neither are any of its congeners, including alkaloid 2.

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
URI: http://hdl.handle.net/1885/159300
Source: European Journal of Organic Chemistry
DOI: 10.1002/ejoc.201700705
Access Rights: Open Access

Download

File Description SizeFormat Image
Total Syntheses of Lycosinine A and Zephycandidine III V6 (Final) AAM.pdf430.67 kBAdobe PDFThumbnail


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  17 November 2022/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator