Total Syntheses of the Amaryllidaceae Alkaloids Zephycandidine III and Lycosinine A and Their Evaluation as Inhibitors of Acetylcholinesterase
The title alkaloids, 1 and 2, have been prepared using cross-coupling chemistries and together with various analogues they have been evaluated for their capacity to inhibit acetylcholinesterase. Contrary to an earlier report, it was found that biaryl 1 is not a significant inhibitor of this enzyme, and neither are any of its congeners, including alkaloid 2.
|Collections||ANU Research Publications|
|Source:||European Journal of Organic Chemistry|
|Access Rights:||Open Access|
|Total Syntheses of Lycosinine A and Zephycandidine III V6 (Final) AAM.pdf||430.67 kB||Adobe PDF|
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