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Improving hox protein classification across the major model organisms

Hueber, Stefanie D; Weiller, Georg F; Djordjevic, Michael; Frickey, Tancred


The family of Hox-proteins has been a major focus of research for over 30 years. Hox-proteins are crucial to the correct development of bilateral organisms, however, some uncertainty remains as to which Hox-proteins are functionally equivalent across different species. Initial classification of Hox-proteins was based on phylogenetic analysis of the 60 amino acid homeodomain. This approach was successful in classifying Hox-proteins with differing homeodomains, but the relationships of...[Show more]

CollectionsANU Research Publications
Date published: 2010-05-25
Type: Journal article
Source: PLoS ONE
DOI: 10.1371/journal.pone.0010820


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