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APOE Genotype and Cardio-Respiratory Fitness Interact to Determine Adiposity in 8-Year-Old Children from the Tasmanian Infant Health Survey

Ellis, Justine A.; Ponsonby, Anne-Louise; Pezic, Angela; Williamson, Elizabeth; Cochrane, Jennifer A.; Dickinson, Joanne L.; Dwyer, Terence

Description

APOE plays a well established role in lipid metabolism. Animal model evidence suggests APOE may also be associated with adiposity, but this has not been thoroughly investigated in humans. We measured adiposity (BMI, truncal fat mass, waist circumference), physical activity (PA), cardiorespiratory fitness and APOE genotype (E2, E3, E4) in 292 8-year-old children from the Tasmanian Infant Health Survey (TIHS), an Australian population-based prospective birth cohort. Our aims were to examine the...[Show more]

CollectionsANU Research Publications
Date published: 2011-11-01
Type: Journal article
URI: http://hdl.handle.net/1885/15896
Source: PLoS ONE
DOI: 10.1371/journal.pone.0026679

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