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Distinct progenitor origin distinguishes a lineage of dendritic-like cells in spleen

Petvises, Sawang; O’Neill, Helen Christine


The dendritic cell (DC) compartment comprises subsets of cells with distinct phenotypes. Previously this lab reported methodology for hematopoiesis of dendritic-like cells in vitro dependent on a murine splenic stromal cell line (5G3). Co-cultures of lineage-depleted bone marrow (Lin(-) BM) over 5G3 continuously produced a distinct population of dendritic-like "L-DC" for up to 35 days. Here the progenitor of L-DC is investigated in relation to known BM-derived hematopoietic progenitors. It is...[Show more]

CollectionsANU Research Publications
Date published: 2014-01-02
Type: Journal article
Source: Frontiers in Immunology
DOI: 10.3389/fimmu.2013.00501


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