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Mitochondrial haplogroups are not associated with diabetic retinopathy in a large Australian and British Caucasian sample

Liu, Ebony; Kaidonis, Georgia; Gillies, Mark C.; Abhary, Sotoodeh; Essex, Rohan; Chang, John H.; Pal, Bishwanath; Daniell, Mark; Lake, Stewart; Gilhotra, Jolly; Petrovsky, Nikolai; Hewitt, Alex W.; Jenkins, Alicia; Lamoureux, Ecosse L.; Gleadle, Jonathan M.; Burdon, Kathryn P.; Craig, Jamie E.


Mitochondrial haplogroups H1, H2 and UK have previously been reported to be associated with proliferative diabetic retinopathy (PDR) in Caucasian patients with diabetes. We aimed to replicate this fnding with a larger sample and expand the analysis to include different severities of DR, and diabetic macular edema (DME). Caucasian participants (n=2935) with either type 1 or type 2 diabetes from the Australian Registry of Advanced Diabetic Retinopathy were enrolled in this study. Twentytwo...[Show more]

CollectionsANU Research Publications
Date published: 2019-01-24
Type: Journal article
Source: Scientific Reports
DOI: 10.1038/s41598-018-37388-8


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