Skip navigation
Skip navigation

Characterization of novel virulence factors of Shigella flexneri and development of Caenorhabditis elegans as an animal model for Shigella infection

George, Divya

Description

The Gram-negative bacterium Shigella flexneri is the causative agent of Shigellosis, also known as bacillary dysentery, responsible for 5-15% of the global burden of diarrhoeal disease. Despite over 50 years of Shigellosis research, the search for a commercially viable vaccine is ongoing. A thorough understanding of bacterial pathogenesis is paramount for the development of an effective vaccine. To this end the aim of this thesis is to further our understanding of S. flexneri pathogenesis by...[Show more]

CollectionsOpen Access Theses
Date published: 2014
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/156384
DOI: 10.25911/5d514a1696e9d

Download

File Description SizeFormat Image
b35790118-George_D.pdf79.28 MBAdobe PDFThumbnail


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator