Skip navigation
Skip navigation

Transmembrane form of tumor necrosis factor : immunobiology and role in infection and inflammation

Tuazon, Ma. Junaliah


Tumor necrosis factor (TNF) is a key cytokine secreted by leukocytes. Although it plays an antimicrobial role in response to infection, many of its effects are detrimental to the host and overproduction is known to lead to pathology. TNF is produced as a transmembrane protein, mTNF, which is proteolytically cleaved to release a secreted form of the protein (sTNF). Of the strategies used by viruses to counter the host, many are directed toward TNF, underscoring the importance of this cytokine...[Show more]

CollectionsOpen Access Theses
Date published: 2013
Type: Thesis (PhD)
DOI: 10.25911/5d5142050abc5


File Description SizeFormat Image
b31265182-Tuazon_M.pdf422.24 MBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator