Synthetic studies of antibiotic natural products
The work detailed in this thesis is directed towards the synthesis of natural products exhibiting antibiotic activity. In antibiotics, we have a readily available means to treat bacterial infection, yet bacterial resistance is increasingly limiting the effectiveness of antibiotics in the clinical setting. With the number of new antibiotics released on the market each year in steady decline, investigation into novel structures that possess potential as antibiotics is urgently needed. Chapter 1...[Show more]
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