Interleukin-1 receptor antagonist as a novel therapeutic target for obesity
Obesity has become one of the most fast-growing economic burdens in the world. It is associated with increased susceptibility to modern diseases, such as diabetes, cardiovascular diseases, and cancer. One of the common physiological changes in obese individuals is a chronic inflammatory state from increased circulating pro-inflammatory cytokines and adipokines, which are secreted from excessive adipose tissue. Human recombinant interleukin-1 receptor antagonist (IL-1Ra), commercially called...[Show more]
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