Chew, Gary Yu Jin
Primary non-congenital antibody defects including common variable immune deficiency (CVID) are the most common forms of primary immune deficiency. These disorders are characterised by recurrent infection as well as immune dysregulation that results in autoimmunity and spontaneous inflammation. This thesis reports research into the mechanisms of primary antibody deficiency, and the intersection between autoimmunity and immune deficiency. The work described was made possible by a national cohort...[Show more]
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