Thiamine utilisation by the malaria parasite Plasmodium falciparum
Thiamine (vitamin B1), is converted into an important cofactor for several enzymes and is an essential nutrient for the human malaria parasite Plasmodium falciparum. The thiamine biosynthesis capacity of the intraerythrocytic stage of P. falciparum is insufficient to meet the parasite's thiamine requirements and, therefore, the parasite needs to scavenge extracellular thiamine in order to support its rapid growth during the erythrocytic stage of its life cycle. Thiamine utilisation by the P....[Show more]
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