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Cellular and serological responses to vaccination in chronic kidney disease

da Silva, Elizabeth


Chronic kidney disease (CKD) and haemodialysis (HD) are associated with an increased risk of hepatitis B infection due to exposure to the virus during haemodialysis, in conjunction with impaired seroconversion to hepatitis B vaccination (HBV). Studies examining augmented vaccine schedules to enhance seroconversion have so far been inconclusive. Furthermore, the cellular defects responsible for impaired vaccine immunity observed in CKD and HD have not yet been...[Show more]

CollectionsOpen Access Theses
Date published: 2018
Type: Thesis (MPhil)
DOI: 10.25911/5c4ad7d577542


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