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Effect of Aspirin on All-Cause Mortality in the Healthy Elderly

McNeil, John J.; Nelson, Mark R.; Woods, Robyn L.; Lockery, Jessica E.; Wolfe, Rory; Reid, Christopher M; Kirpach, Brenda; Shah, Raj C.; Ives, Diane G.; Storey, Elsdon; Ryan, Joanne; Tonkin, Andrew M.; Newman, Anne B.; Williamson, Jeff D.; Margolis, Karen L.; Ernst, Michael E.; Abhayaratna, Walter P.; Stocks, Nigel; Fitzgerald, Sharyn M.; Orchard, Suzanne G.; Trevaks, Ruth E.; Beilin, Lawrence J.; Donnan, Geoffrey A.; Gibbs, Peter; Johnston, Colin I.; Radziszewska, Barbara; Grimm, Richard; Murray, Anne M.


BACKGROUND In the primary analysis of the Aspirin in Reducing Events in the Elderly (ASPREE) trial, now published in the Journal, we report that the daily use of aspirin did not provide a benefit with regard to the primary end point of disability-free survival among older adults. A numerically higher rate of the secondary end point of death from any cause was observed with aspirin than with placebo. METHODS From 2010 through 2014, we enrolled community-dwelling persons in Australia and the...[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
Source: The New England journal of medicine
DOI: 10.1056/NEJMoa1803955
Access Rights: Open Access


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