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Multiphoton imaging for assessing renal disposition in acute kidney injury

Liu, Xin; Liang, Xiaowen; Wang, Haolu; Roberts, Darren; Roberts, Michael S.

Description

Estimation of renal function and drug renal disposition in acute kidney injury (AKI), is important for appropriate dosing of drugs and adjustment of therapeutic strategies, but is challenging due to fluctuations in kidney function. Multiphoton microscopy has been shown to be a useful tool in studying drug disposition in liver and can reflect dynamic changes of liver function. We extend this imaging technique to investigate glomerular filtration rate (GFR) and tubular transporter functional...[Show more]

CollectionsANU Research Publications
Date published: 2016
Type: Conference paper
URI: http://hdl.handle.net/1885/154219
Source: Proceedings of SPIE, Conference Volume 10013
DOI: 10.1117/12.2242964
Access Rights: Open Access

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