Association of FOXD1 variants with adverse pregnancy outcomes in mice and humans
Laissue, P; Lakhal, Besma; Vatin, M; Batista, Frank; Burgio, Gaetan; Mercier, Eric; Dos Santos, Esther; Buffat, Christophe; Sierra-Diaz, Diana Carolina; Renault, G; Montagutelli, Xavier; Salmon, Jane; Monget, Philippe; Veitia, Reiner A; Mehats, Celine; Fellous, Marc; Gris, Jean-Christophe; Cocquet, Julie; Vaiman, Daniel
Recurrent spontaneous abortion (RSA) is a common cause of infertility, but previous attempts at identifying RSA causative genes have been relatively unsuccessful. Such failure to describe RSA aetiological genes might be explained by the fact that reproductive phenotypes should be considered as quantitative traits resulting from the intricate interaction of numerous genetic, epigenetic and environmental factors. Here, we studied an interspecific recombinant congenic strain (IRCS) of Mus musculus...[Show more]
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