Activated platelets rescue apoptotic cells via paracrine activation of EGFR and DNA-dependent protein kinase
Platelet activation is a frontline response to injury, not only essential for clot formation but also important for tissue repair. Indeed, the reparative influence of platelets has long been exploited therapeutically where application of platelet concentrates expedites wound recovery. Despite this, the mechanisms of platelet-triggered cytoprotection are poorly understood. Here, we show that activated platelets accumulate in the brain to exceptionally high levels following injury and release...[Show more]
|Collections||ANU Research Publications|
|Source:||Cell Death & Disease|
|Access Rights:||Open Access|
|01_Au_Activated_platelets_rescue_2014.pdf||4.36 MB||Adobe PDF|
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