Relaxation effect of abacavir on rat basilar arteries
Background The use of abacavir has been linked with increased cardiovascular risk in patients with human immunodeficiency virus infection; however, the mechanism involved remains unclear. We hypothesize that abacavir may impair endothelial function. In addition, based on the structural similarity between abacavir and adenosine, we propose that abacavir may affect vascular contractility through endogenous adenosine release or adenosine receptors in blood vessels. Methods The relaxation...[Show more]
|Collections||ANU Research Publications|
|Source:||PLOS ONE (Public Library of Science)|
|Access Rights:||Open Access|
|01_Li_Relaxation_effect_of_abacavir_2015.pdf||883.1 kB||Adobe PDF|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.