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Computational Evaluation of the Strict Master and Random Template Models of Endogenous Retrovirus Evolution

Nascimento, Fabrícia F; Rodrigo, Allen


Transposable elements (TEs) are DNA sequences that are able to replicate and move within and between host genomes. Their mechanism of replication is also shared with endogenous retroviruses (ERVs), which are also a type of TE that represent an ancient retroviral infection within animal genomes. Two models have been proposed to explain TE proliferation in host genomes: the strict master model (SMM), and the random template (or transposon) model (TM). In SMM only a single copy of a given TE...[Show more]

CollectionsANU Research Publications
Date published: 2016
Type: Journal article
Source: PLOS ONE (Public Library of Science)
DOI: 10.1371/journal.pone.0162454
Access Rights: Open Access


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