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ANALYSIS OF HAIRPIN RNA TRANSGENE INDUCED GENE SILENCING IN FUSARIUM OXYSPORUM

Schumann, Ulrike; Smith, Neil A; Kazan, Kemal; Ayliffe, Michael Anthony; Wang, Ming-Bo

Description

Background: Hairpin RNA (hpRNA) transgenes can be effective at inducing RNA silencing and have been exploited as a powerful tool for gene function analysis in many organisms. However, in fungi, expression of hairpin RNA transcripts can induce post-transcriptional gene silencing, but in some species can also lead to transcriptional gene silencing, suggesting a more complex interplay of the two pathways at least in some fungi. Because many fungal species are important pathogens, RNA silencing is...[Show more]

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
URI: http://hdl.handle.net/1885/153346
Source: Silence: a journal of RNA regulation
DOI: 10.1186/1758-907X-4-3

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