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Rhipicephalus microplus serine protease inhibitor family: Annotation, expression and functional characterisation assessment

Rodriguez-Valle, Manuel; Xu, Tao; Kurscheid, Sebastian; Lew-Tabor, Ala E

Description

Background: Rhipicephalus (Boophilus) microplus evades the host's haemostatic system through a complex protein array secreted into tick saliva. Serine protease inhibitors (serpins) conform an important component of saliva which are represented by a large protease inhibitor family in Ixodidae. These secreted and non-secreted inhibitors modulate diverse and essential proteases involved in different physiological processes. Methods: The identification of R. microplus serpin sequences was performed...[Show more]

CollectionsANU Research Publications
Date published: 2015
Type: Journal article
URI: http://hdl.handle.net/1885/153338
Source: Parasites and Vectors
DOI: 10.1186/s13071-014-0605-4
Access Rights: Open Access

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