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Efficacy of 670 nm Light Therapy to Protect against Photoreceptor Cell Death Is Dependent on the Severity of Damage

Chu-Tan, Joshua; Rutar, Matthew; Saxena, Kartik; Wu, Yunlu; Howitt, Lauren; Valter, Krisztina; Provis, Jan; Natoli, Riccardo


Photobiomodulation at a wavelength of 670 nm has been shown to be effective in preventing photoreceptor cell death in the retina. We treated Sprague-Dawley (SD) rats with varying doses of 670 nm light (9; 18; 36; 90 J/cm2) before exposing them to different intensities of damaging white light (750; 1000; 1500 lux). 670 nm light exhibited a biphasic response in its amelioration of cell death in light-induced degeneration in vivo. Lower light damage intensities required lower doses of 670 nm light...[Show more]

CollectionsANU Research Publications
Date published: 2016
Type: Journal article
Source: International Journal of Photoenergy
DOI: 10.1155/2016/2734139
Access Rights: Open Access


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