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Proteomic analysis of embryonic and young human vitreous

Yee, Kenneth M.P.; Feener, Edward P.; Madigan, Michele C; Jackson, Nicholas J.; Gao, Ben-Bo; Ross-Cisneros, Fred N.; Provis, Jan; Aiello, Lloyd Paul; Sadun, Alfredo A.; Sebag, J.


PURPOSE. The proteomic profile of vitreous from second-trimester human embryos and young adults was characterized using mass spectrometry and analyzed for changes in protein levels that may relate to structural changes occurring during this time. This vitreous proteome was compared to previous reports to confirm proteins already identified and reveal novel ones. METHODS. Vitreous from 17 human embryos aged 14 to 20 weeks gestation (WG) and from a 12-, a 14-, a 15-, and a 28-year-old was...[Show more]

CollectionsANU Research Publications
Date published: 2015
Type: Journal article
Source: Investigative Ophthalmology and Visual Science
DOI: 10.1167/iovs.15-16809
Access Rights: Open Access


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