A generalised module for the selective extracellular accumulation of recombinant proteins
Background: It is widely believed that laboratory strains of Escherichia coli, including those used for industrial production of proteins, do not secrete proteins to the extracellular milieu.Results: Here, we report the development of a generalised module, based on an E. coli autotransporter secretion system, for the production of extracellular recombinant proteins. We demonstrate that a wide variety of structurally diverse proteins can be secreted as soluble proteins when linked to the...[Show more]
|Collections||ANU Research Publications|
|Source:||Microbial Cell Factories|
|Access Rights:||Open Access|
|01_Sevastsyanovich_A_generalised_module_for_the_2012.pdf||2.18 MB||Adobe PDF|
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