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DNA demethylases target promoter transposable elements to positively regulate stress responsive genes in Arabidopsis

Le, Tuan-Ngoc; Schumann, Ulrike; Smith, Neil A; Tiwari, Sameer; Chi Khang Au, Phil; Zhu, Qian-Hao; Taylor, Jennifer; Kazan, Kemal; Llewellyn, Danny; Zhang, Ren; Dennis , Elizabeth S; Wang, Ming-Bo


Background: DNA demethylases regulate DNA methylation levels in eukaryotes. Arabidopsis encodes four DNA demethylases, DEMETER (DME), REPRESSOR OF SILENCING 1 (ROS1), DEMETER-LIKE 2 (DML2), and DML3. While DME is involved in maternal specific gene expression during seed development, the biological function of the remaining DNA demethylases remains unclear. Results: We show that ROS1, DML2, and DML3 play a role in fungal disease resistance in Arabidopsis. A triple DNA demethylase mutant, rdd...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
Source: Genome Biology
DOI: 10.1186/s13059-014-0458-3
Access Rights: Open Access


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