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Specificity of plant microRNA target MIMICs: cross-targeting of miR159 and miR319

Reichel, Marlene; Millar, Anthony A.


Plant microRNA (miRNA) target MIMICs (MIMs) are non-coding RNA transcripts that can inhibit endogenous miRNAs, as they contain a miRNA binding site that forms a three nucleotide (nt) mismatch loop opposite the miRNA cleavage site upon miRNA binding. This loop renders the MIMs non-cleavable, presumably leading to sequestration of the miRNA and thus enabling the endogenous targets to be deregulated. Arabidopsis miR319 and miR159 are two closely related but distinct miRNA families, as they are...[Show more]

CollectionsANU Research Publications
Date published: 2015-05-15
Type: Journal article
Source: Journal of Plant Physiology
DOI: 10.1016/j.jplph.2015.03.010


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