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Hybridization-based reconstruction of small non-coding RNA transcripts from deep sequencing data

Ragan, Chikako; Mowry, Bryan; Bauer, Denis C

Description

Recent advances in RNA sequencing technology (RNA-Seq) enables comprehensive profiling of RNAs by producing millions of short sequence reads from size-fractionated RNA libraries. Although conventional tools for detecting and distinguishing non-coding RNAs (ncRNAs) from reference-genome data can be applied to sequence data, ncRNA detection can be improved by harnessing the full information content provided by this new technology. Here we present NorahDesk, the first unbiased and universally...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/152736
Source: Nucleic Acids Research
DOI: 10.1093/nar/gks505
Access Rights: Open Access

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