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Genetic basis of transcriptome diversity in Drosophila melanogaster

Huang, Wen; Carbone, Mary Anna; Magwire, Michael M; Peiffer, Jason; Lyman, Richard F; Stone, Eric; Anholt, Robert R H; Mackay, Trudy FC


Understanding how DNA sequence variation is translated into variation for complex phenotypes has remained elusive but is essential for predicting adaptive evolution, for selecting agriculturally important animals and crops, and for personalized medicine. Gene expression may provide a link between variation in DNA sequence and organismal phenotypes, and its abundance can be measured efficiently and accurately. Here we quantified genomewide variation in gene expression in the sequenced inbred...[Show more]

CollectionsANU Research Publications
Date published: 2015
Type: Journal article
Source: PNAS - Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.1519159112
Access Rights: Open Access


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