Transient compartmentalization of simian immunodeficiency virus variants in the breast milk of african green monkeys
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Ho, Carrie; Wu, Steven; Amos, Joshua D.; Colvin, Lisa; Smith, Shannon D.; Wilks, Andrew B.; DeMarco, C. Todd; Brinkley, Christie; Denny, Thomas N.; Schmitz, Joern E.; Rodrigo, Allen; Permar, Sallie R.
Description
Natural hosts of simian immunodeficiency virus (SIV), African green monkeys (AGMs), rarely transmit SIV via breast-feeding. In order to examine the genetic diversity of breast milk SIV variants in this limited-transmission setting, we performed phylogenetic analysis on envelope sequences of milk and plasma SIV variants of AGMs. Low-diversity milk virus populations were compartmentalized from that in plasma. However, this compartmentalization was transient, as the milk virus lineages did not...[Show more]
Collections | ANU Research Publications |
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Date published: | 2013 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/152344 |
Source: | Journal of Virology |
DOI: | 10.1128/JVI.01643-13 |
Access Rights: | Open Access |
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01_Ho_Transient_compartmentalization_2013.pdf | 1.05 MB | Adobe PDF |
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