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Ebola viral load at diagnosis associates with patient outcome and outbreak evolution

de La Vega, Marc-Antoine; Caleo, Grazia; Audet, Jonathan; Qiu, Xiangguo; Kozak, Robert A; Brooks, JamesI; Kern, Steven; Wolz, Anja; Sprecher, Armand; Grieg, Jane; Lokuge, Kamalini; Kargbo, David K; Kargbo, Brima; Di Caro, Antonino; Grolla, Allen; Kobasa, Darwyn; Strong, James E; Ippolito, Giuseppe; Van Herp, Michel; Kobinger, Gary


BACKGROUND. Ebola virus (EBOV) causes periodic outbreaks of life-threatening EBOV disease in Africa. Historically, these outbreaks have been relatively small and geographically contained; however, the magnitude of the EBOV outbreak that began in 2014 in West Africa has been unprecedented. The aim of this study was to describe the viral kinetics of EBOV during this outbreak and identify factors that contribute to outbreak progression. METHODS. From July to December 2014, one laboratory in...[Show more]

CollectionsANU Research Publications
Date published: 2015
Type: Journal article
Source: Journal of Clinical Investigation
DOI: 10.1172/JCI83162
Access Rights: Open Access


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