CHD4 Is a Peripheral Component of the Nucleosome Remodeling and Deacetylase Complex
Chromatin remodeling enzymes act to dynamically regulate gene accessibility. In many cases, these enzymes function as large multicomponent complexes that in general comprise a central ATP-dependent Snf2 family helicase that is decorated with a variable number of regulatory subunits. The nucleosome remodeling and deacetylase (NuRD) complex, which is essential for normal development in higher organisms, is one such macromolecular machine. The NuRD complex comprises ∼10 subunits, including the...[Show more]
|Collections||ANU Research Publications|
|Source:||Journal of Biological Chemistry|
|Access Rights:||Open Access|
|01_Low_CHD4_Is_a_Peripheral_Component_2016.pdf||4.72 MB||Adobe PDF|
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