Skip navigation
Skip navigation

Identifying the in vitro interactions between the skeletal muscle ryanodine receptor, triadin and calsequestrin

Wium, Elize

Description

Excitation-contraction coupling (EC coupling) is a process linking depolarization of a muscle fibre membrane with eventual mechanical contraction of that fibre. Key in this process is calcium release into the muscle fibre cytoplasm from an intracellular store (sarcoplasmic reticulum, SR) via a ligand gated calcium channel, the ryanodine receptor (RyR). Numerous proteins engage in RyR regulation to ensure healthy calcium release during EC coupling. One such protein is triadin, which binds both...[Show more]

CollectionsOpen Access Theses
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/151505

Download

File Description SizeFormat Image
b35790878_Wium_E.pdf220.35 MBAdobe PDFThumbnail


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  22 January 2019/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator