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Humoral immunity in secondary poxvirus infection

Tahiliani, Vikas

Description

The studies described in this thesis have utilised the orthopoxvirus ectromelia (ECTV), a natural mouse pathogen that causes a disease termed mousepox, to address the roles of specific innate cell types and T cell subsets in virus control during a secondary infection and more importantly, whether CD4{u207A} T cell help is important for generation of protective recall antibody responses. There are 3 key reasons why the experiments detailed in this thesis were undertaken. First, much of our...[Show more]

CollectionsOpen Access Theses
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/151471

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