Skip navigation
Skip navigation

Directed evolution of glycolytic enzymes : glyceraldehyde-3-phosphate dehydrogenases

Wanty, Christopher James


Glyceraldehyde-3-phosphate dehydrogenase (Gapdh) performs a vital step in glycolysis. An in vitro fermentative system is being developed to convert glucose to ethanol. The system is not cofactor neutral, so will eventually stall through production of adenosine triphosphate (ATP). The Gapdh catalysed step can be modified by use of a non-phosphorylating variant (GapN) of the enzyme. GapN catalyses the Gapdh oxidation and the next step of the pathway without the production of ATP through...[Show more]

CollectionsOpen Access Theses
Type: Thesis (PhD)
DOI: 10.25911/5d51570f8ecca
Access Rights: Open Access


File Description SizeFormat Image
b25698588_Wanty_Christopher James.pdf39.27 MBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  22 January 2019/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator